CFB Week 8 Parlay: SEC matchups, high-scoring Mountain West teams

This is a key time of the year in the 2025 college football season, where teams with playoff aspirations need to avoid losses, and a pair of one-loss SEC teams, LSU and Vanderbilt, will meet in a key showdown in Nashville.

YouBet.com will include the matchup among its favorite plays, recommending the following parlay in Week 8. All lines courtesy of BetMGM and times listed as Eastern Standard Time.

Week 8 CFB Parlay (+596): Vanderbilt -2.5 – Over 63.5 points (UNLV-Boise St.) – Under 51.5 points (Mississippi St.-Florida)

LSU at Vanderbilt, 12 p.m.

LSU's defense is legitimate, but their low-scoring offense exited a sloppy win over South Carolina, where they committed three turnovers. The Gamecocks couldn’t hurt them offensively or slow down the Tigers’ anemic ground game (averaging 112 rushing yards per game; 112th nationally), but Vanderbilt is more effective. Commodores average 42.8 points per game (fourth best nationally) and own 16th-best run defense (99.4 yards per game). They went toe-to-toe with balanced Alabama before giving way in the fourth quarter. Vanderbilt, with a 5-1 record, has had a week to prepare for limited LSU and still has everything to play for; we expect an inspired home performance. 

Pick: Vanderbilt -2.5

UNLV at Boise St., 3 p.m.

UNLV enters 6-0, but they’ve prevailed in four one-score games and rank 92nd in points allowed (29.4). Boise St. isn’t much better, giving up 27.6 points per game, and both teams rely upon high-scoring offenses: the Rebels have scored 38.2 points per game, and the Broncos average 27.6 points. UNLV exits a 51-48 slugfest win over Air Force in which both teams combined for 1,200 yards of total offense. Boise St. needed 21 fourth-quarter points to pull away from a tepid New Mexico squad that scored 25 points despite gaining only 231 total yards last week. A pair of high-powered offenses is going up against soft defenses.

Pick: Over 63.5

Mississippi St. at Florida, 4:15 p.m.

After upsetting Texas at home two weeks ago, Florida followed with an ugly 34-17 loss at Texas A&M. The lack of offensive support (ranked 121st, averaging only 15.8 points) is staggering considering the Gators possess arguably the SEC’s top defense. And they figure to be tested by Mississippi St., which narrowly lost to Tennessee in Week 5 and enters with a respectable 4-2 record. Jeff Lebby’s Bulldogs hang their hat on defense, allowing 23.8 points per game (same as Florida), and both teams will look to control the clock with time-consuming drives.

Pick: Under 51.5