NFL Week 10 Parlay: Packers seek to bounce back in pivotal NFC matchup

The second half of the 2025 NFL regular season is in full swing, and Week 9 features some high-profile divisional matchups. After analyzing the slate, YouBet.com will include a pair among its best bets for a Week 9 parlay wager. All lines courtesy of BetMGM and times listed as Eastern Standard Time.

NFL Week 9 Parlay (+595): Under 48 (Giants-Bears) – Rams -3.5 – Packers -2.5

Giants at Bears, Soldier Field, 1 p.m.

Both teams feature improved offenses and exit high-scoring games, making this easily the highest total from seven meetings this decade. Under is 5-1, lone exception coming in an overtime game, and the Bears and Giants were each held to 20 points two games back. And defense will play a role this week. Bears rank first in turnover differential (+13), and both teams are tied for the fourth-most penalties thrown against this season (83). Wet weather is in the forecast, with the possibility of snow, and teams will look to control the clock with time-consuming drives.

Pick: Under 48

Rams at Niners, Levi’s Stadium, 4:25 p.m.

One of our favorite present betting angles. Since late 2023, the Niners are 1-14 ATS following a straight-up win. They haven’t been good at home over the last 2+ seasons (8-14 ATS), and despite winning last week’s game, the Niners sustained another gut-punching personnel loss, losing impact rookie defensive lineman Mykel Williams (Nick Bosa and Fred Warner also sidelined by season-ending injuries). They may get some players back from a lengthy MASH unit, but Brock Purdy and Brandon Aiyuk remain out. Rams enter with momentum, outscoring opponents by a combined 86-20 margin in three straight wins since a tough three-point home loss to the Niners in Week 5, and the Niners' injury-depleted defense has surrendered at least 24 points in five of the last six games.

Pick: Rams -3.5

Eagles at Packers, Lambeau Field, 8:15 p.m. Monday

Consistency eludes the Packers, but they show up for big games, defeating both divisional leaders on their schedule by double digits so far this year. And they enter a favorable bounce-back spot after losing straight up as a 7+ favorite last week. Teams in this role are 22-13 ATS over the previous three years, and Jordan Love has gone 7-3 ATS in home night games since being named the starter. Eagles enter with a four-game losing streak on Monday night, with Jalen Hurts going 3-6 ATS in his career, and the Packers are 3-0 ATS when laying less than three points this year. The Packers have added motivation, losing three straight to the Eagles since 2021 (they’ve never lost four in a row). 

Pick: Packers -2.5