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NFL Week 15 Parlay: Packers at Broncos in the spotlight

Green Bay Packers quarterback Jordan Love (Photo by Scott Winters/Icon Sportswire)

James Scully headshot
James Scully

December 10th, 2025

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Some lopsided games are expected in Week 15, with six teams favored by 7+ points, but a possible Super Bowl match-up will take place in Mile High City, with the 9-3-1 Packers visiting the 11-2 Broncos. 

YouBet.com will include the anticipated contest among its best bets in the following NFL Week 15 parlay, all lines courtesy of BetMGM and times listed as Eastern.

NFL Week 15 Parlay (+581): Commanders +2.5 – Under 42.5 (Cardinals-Texans) – Packers -2.5

Commanders at Giants, MetLife Stadium, 1 p.m.

Teams exiting a shutout loss are money: 4-0 ATS this year and 34-17-3 ATS since 2015. The Commanders displayed signs of life, narrowly losing back-to-back games to the Dolphins and Broncos, prior to a 31-0 setback at the Vikings last week. After leaving last week’s game early due to elbow soreness, Jayden Daniels will make his second start back and look for the Commanders to generate big plays against a deteriorating Giants defense on the verge of collapse. Giants don’t stop the run, allowing a staggering 533 rushing yards in the last two games, and do nothing well presently behind an interim coaching staff that appears intent on helping their draft status.

Pick: Commanders +2.5

Cardinals at Texans, NRG Stadium, 1 p.m.

Cardinals enter on a five-game skid, scoring less than 18 points in the last two, and must face the NFL’s top-ranked scoring defense, with the Texans allowing a measly 16 points per game. The Texans are also one of the league’s lowest-scoring teams, failing to exceed 20 points in three of their last four wins, and Under 17-5 ATS in C.J. Stroud’s 22 home game starts. Jacoby Brisset has not been good of late, completing only 25 of 44 passes vs the Rams last week, and it promises to be a long afternoon for the Cardinals.

Pick: Under 42.5

Packers at Broncos, Empower Field at Mile High, 4:25 p.m.

After winning 10 straight, the Broncos are receiving points at home vs a Packers team with the third-best record in the NFC. But the Packers are certainly more balanced than the defensive-oriented Broncos, who trailed at some point in their first 12 games before delivering another anemic offensive performance vs the Raiders last week, averaging only 4.9 yards per play as defense and special teams carried them to a 24-17 win. They’ve played a weak schedule. Bo Nix’s stats have declined in his second year, but his receivers play their part, recording 32 drops, the second-most in the league, and the Broncos don’t force a lot of turnovers, entering with a -3 turnover differential. The Packers have shown their chops the last two weeks, winning by seven points over the Lions and Bears, and they’re 10-2 ATS after facing Chicago in the last 12 games. Jordan Love appears to be peaking, and the Packers' offense will prove too much for the Broncos.

Pick: Packers -2.5

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