The Best Soccer Leagues to Bet On (2025 Guide)

Soccer is the world’s most popular sport, and its popularity is only increasing across North America. 

Some of the globe’s most popular leagues can be wagered on in the United States, with huge numbers of fans tuning in to watch matches played in the Premier League, La Liga, and Liga MX. But, what are the best soccer leagues to bet on?

Premier League

The Premier League is the world’s most-watched league, with popular teams such as Liverpool, Manchester United, and Arsenal having massive global fan bases. England’s top flight consists of 20 teams, with each playing against their opponents in home and away matches. 

The team that finishes with the most points is crowned champions, while sides that finish second, third, and fourth secure their progression into the Champions League. 

Important battles for points are staged at both ends of the standings throughout the season, with the bottom three teams suffering relegation to the Championship. 

La Liga

La Liga has a huge global following, which isn’t surprising considering that two of the biggest teams in world soccer play in Spain’s top flight- Barcelona and Real Madrid. 

Matches in the competition are staged on Friday and Monday throughout the season, with the top four teams securing their place in the Champions League. The Spanish top-flight has been home to some of the world’s biggest stars throughout its history, including Cristiano Ronaldo and Lionel Messi. 

That continues in this modern day, as La Liga is the only place to see stars such as Jude Bellingham, Kylian Mbappe, and Robert Lewandowski throughout the season. 

Serie A

Italy’s Serie A is largely considered to be one of the most unpredictable leagues in Europe, with teams such as Juventus, AC Milan, Inter Milan, and Napoli typically competing for the title. 

The competition has been the top level of soccer in Italy since its formation as a round-robin tournament in 1929. 

It is a popular league for soccer betting when it comes to the over/under markets, as it is regarded as one of the best defensive competitions in the world. It is so prestigious that, in a 2017 FourFourTwo publication, 42 of the top 100 players had spent most of their careers in the Italian top-flight. 

MLS

Major League Soccer is the highest level in the United States and has featured some of the biggest names in the sport throughout its history. The league’s popularity reached new heights following the arrival of David Beckham in the 2010s, and Lionel Messi’s move to Inter Miami has once again seen a spike in terms of popularity levels. 

The MLS was founded in 1993, with the first official season taking place in 1996 following the nation’s home World Cup two years earlier. It has been able to compete with some of the major sports in North America, with only the NFL and MLB regularly seeing higher attendance figures. 

In fact, the MLS ranks second only to the Premier League in terms of being the most attended soccer league in the world. 

Liga MX

Mexico’s Liga MX is the second-most watched soccer league in the United States, with only the Premier League averaging higher television viewership. 

The competition has been Mexico’s top soccer division since 1943, with two short tournaments making up the campaign. The Apertura runs from July to December, before the Clausura is staged between January and May. 

Its competitive nature ensures that it is one of the most popular betting leagues in world soccer, with the unpredictable nature ensuring value when making selections. 

Popular Soccer Betting Markets

Betting on the world’s best leagues is exceptionally popular. You can find out more about the prominent markets that are available at online sportsbooks below:

• Moneyline: Bets can be placed on the outcome of matches after 90 minutes. Returns are awarded based on selections, with winnings awarded if bettors are correct.
• Over/Under: Bettors can wager on the total number of goals, corners, and cards.
• Both Teams to Score: Bets can be placed on whether both teams will score in 90 minutes.