NFL Week 5 Parlay: Rookie road test for Giants, Eagles face defensive stalwart
October 1st, 2025
Only two teams remain unbeaten after Week 4 in the 2025 NFL season, the Super Bowl champion Eagles and Bills, and four teams (Bears, Falcons, Packers, and Steelers) will begin their bye in Week 5. YouBet.com has scoured the slate and selected the following parlay in Week 5, all lines courtesy of BetMGM and times listed in Eastern Standard Time.
Week 5 NFL Parlay (+595): Saints ()-Under points (Broncos at Eagles)-Titans ()
Giants at Saints, Caesars Superdome, 1 p.m.
The Saints opened 0-4 against a tough slate, facing playoff contenders in their last three (49ers, Seahawks, and Bills), and they’ve been in every game but one, mostly due to defense. But Kellen Moore’s offense showed progress last week, recording more first downs and plays as they took the Bills to the wire on the road. The Giants eked out an emotional, three-point win in Jaxson Dart’s debut last week, but the rookie threw for only 111 yards, including 20 to injured Malik Nabors, who the Giants will miss dearly. The Saints’ run defense has allowed only 111 rushing yards per game (11th-best) in a pair of home games; they’re eligible to stifle the Giants’ run game and keep Dart in check in his first road test.
Pick: Saints
Broncos at Eagles, Lincoln Financial Field, 1 p.m.
A winner in 21 of their last 22 games, the Eagles are a machine and have adopted an “if it ain’t broke, don’t fix it” mentality on offense, playing conservatively to avoid turnovers when possible. They cranked it up offensively at times when recording narrow wins over the Chiefs and Rams, but have employed a mostly pedestrian approach, logging only 200 totals and 3.4 yards per play in a 31-25 win over the Buccaneers last week. The Eagles rank 30th in total offense and 31st in passing. The Broncos have yet to score more than 28 points in a game and rely heavily on their defense. Projecting a slugfest between two elite stop units.
Pick: Under points
Titans at Cardinals, State Farm Stadium, 4:05 p.m.
Kyler Murray and Marvin Harrison Jr. lack chemistry, and a season-ending injury to leading rusher and team leader James Conner in Week 3 put the Cardinals out of sync. The Cardinals rallied late to make it interesting before losing in overtime last week, but they were held to 253 yards, had seven penalties accepted, and lost a pair of turnovers. The Titans haven’t been competitive against teams that have been rolling offensively the last three weeks. They played a sluggish Broncos offense tight in Week 1 (losing by one score) and face another dysfunctional offense in Week 5. Cam Ward, who played well at times vs the Rams and Colts in Weeks 2 & 3, can bounce back after a dismal showing in Week 4, and all four Cardinals games have been decided by five points or less.
Pick: Titans
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