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How to Bet on MLS: Major League Soccer Betting Guide (2025)

Man holding money to bet on a soccer game going on in the background.

Man holding money to bet on a soccer game going on in the background. (Photo credit to Shutterstock)

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YouBet Staff

May 21st, 2025

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The MLS is the highest level of soccer competition in North America, with 30 teams from across Canada and the United States involved. 

The league's popularity reached new heights in the 2010s when superstars such as David Beckham, Steven Gerrard, and David Villa moved to the league. It now ranks as the fourth-most attended sporting competition in the United States, and only the Premier League ranks higher in attendance figures in global soccer competitions. 

Betting on the action is incredibly popular, and you can find out everything you need to know when making MLS wagers here. 

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Common Bet Types and How to Bet on MLS

Betting on the MLS is incredibly popular, and there is a wide range of markets available to gamblers online. You can find out more about some of the prominent bet types here. 

Moneyline Betting

Betting on the moneyline is the most straightforward way to make selections on MLS matches. Here, the bettor will aim to correctly predict the outcome after 90 minutes. 

Three options are available in this market: both teams and the draw. For example, if you make a bet on Inter Miami to beat Nashville, then the returns will be awarded should the selection win inside 90 minutes. If the match ends in a draw or Nashville wins, the stake is lost. 

Spread Betting

Like other North American sports, betting on the spread is popular when making selections on the MLS. Here, the favored team will start at a disadvantage, signalled by the ‘-‘. 

Meanwhile, unfavored teams could also start with a head start, shown by the ‘+’. For example, if you bet on Los Angeles FC to win a match against Los Angeles Galaxy with a -1 disadvantage, then LAFC must win the match by two clear goals for the bet to win. 

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Over/Under Betting

If you’re looking to make a bet on the MLS that doesn’t revolve around the match result, then you can opt to wager on the over/under markets. Here, the sportsbook will set a benchmark in terms of goals, cards, or corners, and the bettor will be wagering on whether there will be higher or lower. 

For example, if there is a benchmark at 2.5 goals, a bet can be placed on over 2.5 goals if you believe that at least three match goals will be scored in 90 minutes. If there are two or fewer goals, then the stake is lost. 

Double Chance Betting 

Bettors can opt to take a chance on an outsider when making selections on MLS matches. The Double Chance market enables gamblers to cover two possible outcomes to increase their chances of getting returns. 

For example, in a match between the New York Red Bulls and D.C. United, a bettor can cover the Bulls and draw. Here, returns are awarded provided that United doesn't win the match in 90 minutes. 

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Props Betting

One of the most engaging betting markets online can be found in the props selection. Here, bettors can have creative freedom when making selections, including player markets, such as first scorer, a player to be carded, and even players that will concede fouls. 

Props bets are incredibly popular, as they allow experienced gamblers the opportunity to put their extensive research to good use. 

Outright Betting

In addition to single-match betting, gamblers can also make selections on season-long markets in the outright section. A bet can be placed here on the team winning the MLS Cup. 

It is an excellent market to remain engaged in the competition throughout the season, with the returns awarded once the season has concluded. However, finding the best time to get value is essential, as prices will change regularly throughout the season depending on how teams perform. 

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